Dermal Models
MLM Medical Labs specializes in dermal research with a host of validated preclinical models and translational services supported by a range of read-outs including protein and mRNA analyses, histology and flow cytometry.
Validated models include:
Imiquimod (IMQ) induced Psoriasis Model
- IL-23-induced Psoriasis Model
- Fluorescein Isothiocyanate (FITC) and Dinitrochlorobenzene (DNCB) Contact Dermatitis
- Oxazolone-induced Delayed Type Hypersensitivity (DTH) Model
- Passive Cutaneous Anaphylaxis Model
- MC903-induced Atopic Dermatitis
Available readouts:
- Clinical score
- Ear thickness
- Biomarker analysis (mRNA or protein)
- Cell populations in spleen/lymph nodes by flow cytometry
- Histology/IHC
- PK blood collections
Are you interested in a variation of a model or a new paradigm?
Our scientists are passionate about the development of new models! We often participate in opportunities for co-development and pilot programs to establish new models and reach new levels of understanding.
